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Defining the Cardiometabolic Profile of Transgender Boys and Men

Studying the cardiometabolic impact of testosterone therapies on transgender boys and men to advance their health and wellbeing

Full Project Name:Defining the Cardiometabolic Profile of Transgender Boys and Men on Testosterone TherapyPrincipal Investigator:Susanne M. Cabrera, MD, PediatricsCo-Investigator:Michael Widlansky, MD, MPH, Medicine; Andrew Petroll, MD, MS, Medicine; Kristen Klement, MD, Plastic SurgeryAward Amount:$250,000
Award Date
July2021
Project Duration:36 months

Project Updates:


  • Continuing to conduct recruitment of participants with over half of the intended number of participants recruited and maintaining low participant attrition rates
  • Continuing to obtain breast tissue samples from the MCW Tissue Bank to perform estrogen-stimulated vasoreactivity studies on endothelium obtained from transmasculine individuals on long-term testosterone therapy, cisgender women undergoing breast reduction surgery, and cisgender men undergoing gynecomastia surgery to determine difference in gene expression
  • Submitted two abstracts to large, well-attended international conferences

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