Systematic Analysis of Molecular Pathways Implicated in Amyotrophic Lateral Sclerosis

Project Description Narrative:

Amyotrophic lateral sclerosis (ALS) is the most common form of motor nerve cell disease. It causes muscle weakness, paralysis, and death within two to five years of diagnosis. ALS places enormous financial and emotional strain on patients and families. No treatments that currently exist go beyond relieving symptoms to resist the underlying causes of the disease.

Through a better understanding of the genes involved in ALS, the researchers aim to find new ideas for interrupting the progression of ALS that can be turned into potential therapies.