Leveraging a New Translational Metabolomics Resource to Identify Cancer Pathways and Signatures

Project Updates:

• Completed installation of Bruker imaging MS systems for spatial omics analysis in the facility space
• Received an MCW instrumentation upgrade grant to expand LC-MSn (liquid chromatography-mass spectrometry) capability for in-depth structural characterization of biomolecules
• Developed several collaborative and service projects with multiple investigators at MCW focused on human disorders to illustrate the biomolecular expression in brain cancer, pancreatic cancer, acute myeloid leukemia, Lyme disease, lysosomal diseases, and others
• Analyzed tissue samples for users, developed several collaborative projects for spatial Omics, and supported users to prepare NIH grant submissions that require imaging MS
• Published two papers supported by the AHW funds