Investigating the relationship between the developing immune system and microbiomes to advance prevention and care
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Engineered a strain of bacteria to allow the team to investigate immune responses
Created mice with a specific defect in immune regulation and showed that the mice have very early onset bowel inflammation
Demonstrated that byproducts produced by intestinal microbes change both gut development and production of intestinal antimicrobials via a novel pathway
Developed novel approaches to analyze small-volume blood samples from NICU patients
Disseminated findings through three published manuscripts and two academic presentations
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