Establishing an integrated clinical and translational pancreatic cancer research program at the Medical College of Wisconsin
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Established the Pancreatic Cancer Research Program and began creation of a novel clinical trial of personalized therapy for patients with localized pancreatic cancer
Established the infrastructure to obtain and profile pancreatic cancer tissues in a non-invasive manner for molecular profiling
Designed and implemented a clinical trial utilizing the molecular profiling techniques to guide the selection of chemotherapy for patients with localized pancreatic cancer, becoming the first trial opened in the United States which used a personalized approach for localized pancreatic cancer. Began accrual of subjects into the clinical trial and added the University of Cincinnati as a second site
Initiated a collaboration to examine the use of cell-free DNA as a biomarker for treatment response
Supported work by Dr. Susan Tsai to establish a pancreatic xenograft model for tumor expansion which has subsequently generated over 20 novel pancreatic cancer cell lines, establish a Rapid Autopsy Program for pancreatic cancer, and establish a screening clinic for high-risk familial pancreatic cancer patients
Disseminated findings through various publications and presentations
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