Establishing Wisconsin's First Cancer Precision Medicine Simulation Unit

Transforming and advancing the interpretation of cancer-associated gene mutations

Full Project Name:Establishing Wisconsin's First Cancer Precision Medicine Simulation UnitPrincipal Investigator:Raul Urrutia, MD, Genomic Sciences and Precision Medicine CenterAward Amount:$4,000,000
Award Date
February2019
Project Duration:60 months

Project Description Narrative:


In the field of precision medicine, simulations are critical in order to deal with human material, as experimentation on humans is not possible. By establishing the first Precision Medicine Simulation Unit (PMSU) in the state of Wisconsin, the Medical College of Wisconsin's Genomic Sciences and Precision Medicine Center aims to advance the interpretation of cancer-associated gene mutations and ultimately develop powerful tools to fight these diseases.

Through this award, MCW's Genomic Sciences and Precision Medicine Center will establish the first PMSU in Wisconsin. developing the tools to process cancer genomics data, supporting experimental assays, and enhancing tools available to researchers and medical practice for interpreting genomics data.

Project Updates:


  • Continue efforts leading to the discovery of new methods of interpretation of pancreatic cancer associated mutations
  • Established connections with NIH, Mayo Clinic, Spain, France, and Italy, which have grown the national and international reputation of Wisconsin's First Precision Medicine Simulation Unit
  • Completed the integration of the chemical biology activities necessary for benchmarking the project's methods, to a state-of-the-art Structural Genomic Unit, located at GSPMC
  • Produced a large amount of data through the Structural Genomic Unit that has directly led to grant submissions and publications
  • Completed the integration of the Functional Validation Group that uses genetically engineered cells and animal models to benchmark the predictions derived from new methods in data science

AHW Logo

8701 W Watertown Plank Road,
Milwaukee, WI 53226-0509
(414) 955-4350

©2021 MEDICAL COLLEGE OF WISCONSIN. ALL RIGHTS RESERVED | MCW.EDU | TERMS & PRIVACY | NON-DISCRIMINATION NOTICE

top